Recommanded Product: 3235-67-4. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 1-Piperidineacetic Acid, is researched, Molecular C7H13NO2, CAS is 3235-67-4, about Acute toxicity and depressive effect on spontaneous motor activity of piperidine N-derivatives in mice. Author is Kimura, Katsuhiko; Yoshida, Masahumi; Nagaoka, Masao; Ohgiya, Shozaburo.
The acute toxicity and depressive effect on spontaneous motor activity of the title compounds I (R = CH2CO2H, CH2CH2OH, etc.) were examined using mice untreated and pretreated with phenobarbital and SKF-525A. The acute toxicity of I decreased and its depressive effect increased following enzyme induction, whereas following enzyme inhibition the opposite occurred. Structure-activity relations are discussed.
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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem