In heterogeneous catalysis, the catalyst is in a different phase from the reactants. Formula: C4H2ClNO2, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 62348-13-4, name is Isoxazole-5-carbonyl chloride. In an article，Which mentioned a new discovery about 62348-13-4
Antagonism of cannabinoid-1 (CB1) receptor signaling has been demonstrated to inhibit feeding behaviors in humans, but CB1-mediated central nervous system (CNS) side effects have halted the marketing and further development of the lead drugs against this target. However, peripherally restricted CB1 receptor antagonists may hold potential for providing the desired efficacy with reduced CNS side effect profiles. In this report we detail the discovery and structure-activity-relationship analysis of a novel bicyclic scaffold (3) that exhibits potent CB1 receptor antagonism and oral activity in preclinical feeding models. Optimization of physical properties has led to the identification of analogues which are predicted to have reduced CNS exposure and could serve as a starting point for the design of peripherally targeted CB1 receptor antagonists.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 62348-13-4, help many people in the next few years.Formula: C4H2ClNO2
Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem