The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Trimethylphosphineoxide( cas:676-96-0 ) is researched.Safety of Trimethylphosphineoxide.Zhou, Yousheng; Mei, Xingyu; Cai, Zhe; Wang, Qing; Duanmu, Jiahui; Kai, Ouyang; Zhang, Haijiang; Tanga, Xiujuan; Han, Xiaoxiang published the article 《An efficient and recyclable sn-based phosphotungstic acid with tunable bronsted/lewis acidity for selective oxidation of benzyl alcohol》 about this compound( cas:676-96-0 ) in Journal of the Brazilian Chemical Society. Keywords: tin phosphotungstic acid benzyl alc Bronsted Lewis acidity oxidation. Let’s learn more about this compound (cas:676-96-0).
A series of metal ion (M = Sn2+, Fe3+, Ni2+, Co2+, Ag+, Cu2+) exchanged tungstophosphoric acid (H3PW12O40; TPA) catalysts with tunable Bronsted/Lewis acidity were synthesized and exploited for the oxidation of benzyl alc. (BzOH) to benzaldehyde (BzH) using hydrogen peroxide (H2O2) as oxidant. The structure of these M-TPA composite salts was also characterized by Fourier transform IR spectroscopy (FTIR), X-ray diffraction (XRD), thermogravimetric analyses (TGA) and solid-state 31P NMR (NMR) probe mol. method. Among these M-TPAs, the Sn1/2H2PW12O40 catalyst, which presented strong Bronsted acidity, the synergistic effect of Bronsted/Lewis and pseudo-liquid characteristic property, exhibited excellent catalytic activity and durability with 98.2% of BzH selectivity and 95.1% of BzH yield. The optimal conditions for the oxidation of BzOH optimized by response surface methodol. (RSM) were as follows: n(BzOH)/n(H2O2) = 1:1.25, catalyst amount of 5.5 weight% to BzOH, water amount of 17 mL, 3.3 h of reaction time, and temperature 393 K. Moreover, further kinetic study confirmed that the reaction order was 2.64 and the activation energy was 21.75 kJ mol-1.
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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem