Electric Literature of 90924-12-2, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 90924-12-2, Name is (3-Phenyl-5-isoxazolyl)methanol,introducing its new discovery.
This invention provides thieno[2,3-d]pyrimidine derivatives containing isoxazole heterocycle represented by formula (I), or pharmaceutically acceptable salts thereof Wherein: R1 and R2 may be the same or different and is independently to each other selected from H, C1-6 alkyl, C1-6 alkoxy, halo-C1-6 alkyl or halo-C1-6 alkoxy, aryl group optionally substituted by R7 or heteroaryl group optionally substituted by R8; or R1 and R2 together with the carbon atoms to which they are attached, may form a 4- to 6-membered carbocyclic ring or heterocyclic ring; said carbocyclic ring or heterocyclic ring is optionally substituted by H, C1-6 alkyl, halogen, nitro, or amino; said heterocyclic ring contains at least one heteroatom selected from N, O or S; Z is -NR6-, C(R6)2, -S- or -O-, in which R5 is H or C1-6 alkyl, and R6 is the same or different, selected from H, C1-6 alkyl or hydroxyl substituted C1-6 alkyl; R3 is selected from H, halogen, C1-6 alkyl, C1-6 alkoxy, halo-C1-6 alkyl or halo-C1-6 alkoxy; n is an integer of 0-5; R4 is selected from H, C1-6 alkyl, C1-6 alkoxy or halo-C1-6 alkyl, aryl group optionally substituted by R9, or heteroarylgroup optionally substituted by R10; R7, R8, R9 or R10 independently to each other, is selected from H, hydroxy, mercapto, cyano, amino, nitro, halogen, C1-6 alkyl, C1-6 alkoxy, C1-6 alkylthio, carboxy, halo-C1-6 alkyl or halo-C1-6 alkoxy. This invention also provides the preparation method and medicinal uses of the compounds of formula (I) and pharmaceutically acceptable salts thereof. and this class of compounds can be used as medicants or lead compounds for the treatment of diseases such as tumors, cancers.
We’ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 90924-12-2, and how the biochemistry of the body works.Reference of 90924-12-2
Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem