62348-13-4, Isoxazole-5-carbonyl chloride is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
62348-13-4, Under a nitrogen atmosphere,Benzo[b]thiophene-6-ol (Compound 1) (5.86 g, 39.01 mmol),After 4-dimethylaminopyridine DMAP (473 mg, 3.87 mmol) was dissolved together in THF (100 mL),Additional triethylamine (4.15 g, 41.03 mmol) and isoxazole-5-acyl chloride (Compound 2) (40.99 mmol),The mixture was heated to reflux for 7 hours and then the reaction was cooled to 50 C.A mixture of water (20 mL) and acetic acid (3.67 mL) was added.A layered solution was obtained.The organic layer is separated and the aqueous layer is discarded to obtain a THF solution of benzo[b]thiophene-6-isoxazole-5-carboxylate (Compound 3), which is directly used in the next synthesis. .
The synthetic route of 62348-13-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Wang Liping; (11 pag.)CN108516972; (2018); A;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem