3445-52-1, 5-Methylisoxazole-3-carboxamide is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
EXAMPLE 1 STR80 2.52 g (0.02 mol) of 5-methyl-isoxazole-3-carboxamide are dissolved in 50 ml of 1,4-dioxane and after adding 3.4 g (0.06 mol) of powdered potassium hydroxide the mixture is stirred at 80 C. for 30 minutes. The mixture is cooled, 5.7 g (0.022 mol) of methyl 2-chlorosulphonylbenzoate are added at room temperature for 20 hours. The solvent is then distilled off in vacuo, the residue is taken up in water and the solution is filtered. The product precipitates from the filtrate on acidifying with hydrochloric acid, and is collected on a suction filter and dried on clay. 1.8 g (27% of theory) of N-(2-methoxycarbonylphenylsulphonyl)-5-methyl-isoxazole-3-carboxamide of melting point 101 C. are obtained.
3445-52-1, The synthetic route of 3445-52-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Bayer Aktiengesellschaft; US5256632; (1993); A;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem