Bondock, Samir’s team published research in Journal of Heterocyclic Chemistry in 51 | CAS: 1076-59-1

Journal of Heterocyclic Chemistry published new progress about 1076-59-1. 1076-59-1 belongs to isoxazole, auxiliary class Oxazoline,Benzene,Ester, name is 3-Phenylisoxazol-5(2H)-one, and the molecular formula is C9H7NO2, Formula: C9H7NO2.

Bondock, Samir published the artcileA Convenient Synthesis of 2H-Pyran-2-ones, Fused Pyran-2-ones, and Pyridones Bearing a Thiazole Moiety, Formula: C9H7NO2, the publication is Journal of Heterocyclic Chemistry (2014), 51(1), 249-255, database is CAplus.

The versatile enaminonitrile, 2-cyano-3-(dimethylamino)-N-(4-phenylthiazol-2-yl)acrylamide (I), reacts with some C,O-binucleophiles (acetylacetone and dimedone) in refluxing acetic acid to afford the pyranone II, the chromene III, and with C,N-binucleophiles (2-(benzothiazol-2-yl)acetonitrile and 2-(1H-benzimidazol-2-yl)acetonitrile) to afford the resp. 1H-pyrido[2,1-b]benzothiazole and pyrido[1,2-a]benzimidazole derivatives Similar treatment of I with phenol, resorcinol, α-naphthol, and β-naphthol in boiling acetic acid gave the coumarin derivatives The utility of enaminonitrile I for the synthesis of 6H-pyrano[3,2-d]isoxazole, pyrano[2,3-c]pyrazole, and pyrano[2,3-d]pyrimidine derivatives was also explored via its reaction with 3-phenylisoxazol-5(4H)-one, 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one, and barbituric acid, resp. The mechanistic aspects for the formation of the new compounds were also discussed.

Journal of Heterocyclic Chemistry published new progress about 1076-59-1. 1076-59-1 belongs to isoxazole, auxiliary class Oxazoline,Benzene,Ester, name is 3-Phenylisoxazol-5(2H)-one, and the molecular formula is C9H7NO2, Formula: C9H7NO2.

Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem