Bertaccini, G.; Impicciatore, M.; Vitali, T. published the artcile< Pharmacological activities of benzisothiazolone and benzisoxazolone>, Safety of Benzo[d]isoxazol-3-ol, the main research area is benzisoxazolinone antiinflammatory analgesic antipyretic; benzisothiazolinone antiinflammatory analgesic antipyretic; toxicity benzisothiazolinone benzisoxazolinone.
1,2-Benzisoxazolin-3-one (I) [21725-69-9] and 1,2-benzisothiazolin-3-one (II) [2634-33-5] were more potent antiinflammatory, analgesic, and antipyretic agents than salicylamide and less potent than phenylbutazone when tested in rats, mice, and rabbits; II was generally more potent than I. The acute oral LD50 values for I and II in mice were 2,650 and 1,020 mg/kg, resp.
Pharmacological Research Communications published new progress about Analgesics. 21725-69-9 belongs to class isoxazole, and the molecular formula is C7H5NO2, Safety of Benzo[d]isoxazol-3-ol.
Referemce:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem