446292-10-0, Name is (S)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one, molecular formula is C14H17N3O4, belongs to Isoxazoles compound, is a common compound. In a patnet, author is Zhu, Ning, once mentioned the new application about 446292-10-0, Computed Properties of C14H17N3O4.
Selective reduction of 4-substituted 3-aryl-5-trifluoromethylisoxazole by NaBH4
A series of 4-substituted 3-aryl-5-trifluoromethyl-4,5-dihydroisoxazole derivatives was synthesized by selective reduction of the corresponding 3-aryl-5-trifluoromethyl-4-isoxazole with NaBH4 under various reaction conditions. It was found that the reduction selectivity of endocyclic carbon-carbon double bond of the isoxazole ring was strongly dependent on the electronic effects of substituents at C-4 of trifluoromethylated isoxazoles. Meanwhile, the solvent effects also had a great influence on the reduction selectivity of endocyclic carbon carbon double bond of the 4-iminoyl substituted isoxazole ring.
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Reference:
Isoxazole – Wikipedia,
,Isoxazole | C3H3NO – PubChem