Synthetic Route of 1072-67-9, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1072-67-9, Name is 5-Methylisoxazol-3-amine, molecular formula is C4H6N2O. In a Article，once mentioned of 1072-67-9
A series of alpha-amino (2, or 4)-fluorobenzyl-phosphonates containing isoxazole moiety were synthesized by the reaction of fluorobenzoaldehyde, 3-amino-5-methylisoxazole and dialkyl phosphite under unltrasound irradiation without solvent and catalyst. Their structures were established by elemental analysis, IR, 1H NMR and 13C NMR. The bioassay tests showed that these title compounds exhibit moderate anticancer activity in vitro by MTT method. The crystal structure of 4c has been determined by X-ray diffraction. It crystallizes in the monoclinic system, space group P2(1)/n, with unit cell parameters: a = 0.9335(3), b = 1.3067(4), c = 1.6552(6) nm, beta = 104.801(6), Z = 4, V = 1.9521(11) nm3, Dc = 1.260 g/cm3, mu = 0.172 mm-1, F(000) = 784. The crystal structure was solved by direct methods and refined by full-matrix least squares to final values of R = 0.0524 and wR = 0.1592 with 9902 reflections (I > 2sigma(I)). The dihedral angle between the plane of isoxazole group and the plane of the benzene is 77.27.
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Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem