Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. SDS of cas: 90924-12-2. Introducing a new discovery about 90924-12-2, Name is (3-Phenyl-5-isoxazolyl)methanol
One-pot synthesis of 3,5-disubstituted isoxazoles from propargylic alcohols through propargylic N-hydroxylamines
An efficient approach has been described for the synthesis of 3,5-disubstituted isoxazoles from propargylic alcohols. The strategy involves a one-pot p-TSA-catalyzed N-propargylation of protected hydroxylamines followed by a TBAF-mediated detosylative 5-endo-dig cyclization. The method was successfully used for the synthesis of various 3,5-disubstituted isoxazoles.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.SDS of cas: 90924-12-2, you can also check out more blogs about90924-12-2
Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem