Synthetic Route of 288-14-2, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.288-14-2, Name is Isoxazole, molecular formula is C3H3NO. In a Review，once mentioned of 288-14-2
Hit identification is a crucially important stage gate in the drug discovery process. As the development candidate that emerges from pre-clinical research invariably resembles the initial hit, it is important to make as well-informed a choice as possible when selecting which hits to progress and which to shelve. Decisions made during the hit identification process determine the chemistry direction in which a project proceeds, usually taking into account the potency of the hit, any SAR generated during the hit-finding exercise, the potential scope for generating novel and patentable chemical matter, and the synthetic tractability of the series. Over the last decade, a huge amount of financial and intellectual investment has been made in HTS to identify compounds with low micromolar IC50s, leading to major advances in combinatorial chemistry, high throughput analysis and purification, and compound handling and storage. HTS is constantly improving as the processes are refined and compound collections are improved, but overall results have been disappointing. Recently, structure-guided approaches have been used much more frequently at the hit-finding stage of drug discovery and, as this review seeks to demonstrate, these approaches have had a major impact on a number of kinase targets. The closer integration of these tools, combined with ongoing technological advances in computational chemistry, X-ray crystallography and NMR spectroscopy will inevitably lead to an even greater use of structural techniques for hit generation to complement or replace HTS.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 288-14-2
Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem