Application of 84746-24-7

Compound(84746-24-7)Category: isoxazole received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(2-[4-(Pyrimidin-2-yl)piperazin-1-yl]pyrimidine), if you are interested, you can check out my other related articles.

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Journal of Pharmaceutical and Biomedical Analysis called Analysis of new serotonergic anxiolytics by liquid chromatography, Author is Farina, A.; Doldo, A.; Quaglia, M. G., which mentions a compound: 84746-24-7, SMILESS is C1(N2CCN(C3=NC=CC=N3)CC2)=NC=CC=N1, Molecular C12H14N6, Category: isoxazole.

A simple isocratic procedure was developed for the anal. of new serotonergic anxiolytics and related compounds in bulk, pharmaceuticals, and in biol. samples. The system may be applied for the assay of other serotonergic anxiolytics of related structure such as buspirone. The HPLC assay utilized a reversed-phase C18 column, a mobile phase consisting of a mixture (55:45) of (A) buffer potassium dihydrogen phosphate (0.05M) containing sodium lauryl sulfate (0.005M) and (B) MeCN. A fluorescence detection was used with λex 237 nm; λem 374 nm. The accuracy, precision and sensitivity of the proposed method were established. Standard curves were linear with respect to concentration in the range 0.05-7.5 μg mL-1. The method also allowed the separation and identification of related compounds at concentrations <0.01%. Compound(84746-24-7)Category: isoxazole received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(2-[4-(Pyrimidin-2-yl)piperazin-1-yl]pyrimidine), if you are interested, you can check out my other related articles.

Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem