Analyzing the synthesis route of 1228689-61-9

The synthetic route of 1228689-61-9 has been constantly updated, and we look forward to future research findings.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1228689-61-9,Methyl 5-(4-bromophenyl)-3-methylisoxazole-4-carboxylate,as a common compound, the synthetic route is as follows.

Lithium hydroxide (2g, 47.7mmol) was added to a solution of 5-(4-bromo-phenyl)-3-methyl- isoxazole-4-carboxylic acid methyl ester (7g, 23.6mmol) in MeOH (5OmL) and H2O (1OmL), and the reaction was stirred at 6O0C for 1 hour. Acidic work-up the title compound., 1228689-61-9

The synthetic route of 1228689-61-9 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; AMIRA PHARMACEUTICALS, INC.; HUTCHINSON, John Howard; SEIDERS, Thomas Jon; WANG, Bowei; ARRUDA, Jeannie M.; ROPPE, Jeffrey Roger; PARR, Timothy; WO2010/141761; (2010); A2;,
Isoxazole – Wikipedia
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