In heterogeneous catalysis, the catalyst is in a different phase from the reactants. category: Isoxazoles, At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 288-14-2, name is Isoxazole. In an article£¬Which mentioned a new discovery about 288-14-2
Recent advancements in 1, 4-disubstituted 1h-1, 2, 3-triazoles as potential anticancer agents
Cancer is a class of formidable disease with high degree of mortality. Despite much progress in chemotherapy, the problem of drug resistance has led to the search for newer leads with superior efficacy. 1, 2, 3-Triazoles are among a vast number of nitrogen containing heterocycles studied extensively as pharmacologically important scaffolds. Recently developed copper (I)-catalyzed cycloaddition reaction between organic azides and terminal alkynes yielding 1, 4-disubstituted 1, 2, 3-triazoles has attracted considerable attention because it allows the construction of a vast array of 1, 2, 3-triazoles with significant potential in pharmaceutical chemistry. In this article, an attempt to summarize the wide range of anticancer agents derived from copper (I)-catalyzed azide alkyne cycloaddition reported by the authors worldwide, has been made. This review includes articles published from 2010 onwards and summarizes the recent progress on the development of 1, 4-disubstituted 1H-1, 2, 3-triazoles as novel anticancer chemotypes with high therapeutic indices.
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Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem