Downstream synthetic route of 62348-13-4

As the paragraph descriping shows that 62348-13-4 is playing an increasingly important role.

62348-13-4,62348-13-4, Isoxazole-5-carbonyl chloride is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: To a stirred solution of 9f (100 mg, 0.32 mmol) in DMA (3 mL) was added 3-fluorobenzoyl chloride (43 muL, 0.36 mmol), and the mixture was stirred at room temperature overnight. The mixture was diluted with water and extracted with EtOAc. The organic layer was washed with water and brine, dried over MgSO4, and filtered. The filtrate was concentrated in vacuo, and the residue was purified by basic silica gel column chromatography (n-hexane/EtOAc 100:0 to 0:100) to give 10f (56 mg, 40%) as a white solid.

As the paragraph descriping shows that 62348-13-4 is playing an increasingly important role.

Reference£º
Article; Miyamoto, Naoki; Sakai, Nozomu; Hirayama, Takaharu; Miwa, Kazuhiro; Oguro, Yuya; Oki, Hideyuki; Okada, Kengo; Takagi, Terufumi; Iwata, Hidehisa; Awazu, Yoshiko; Yamasaki, Seiji; Takeuchi, Toshiyuki; Miki, Hiroshi; Hori, Akira; Imamura, Shinichi; Bioorganic and Medicinal Chemistry; vol. 21; 8; (2013); p. 2333 – 2345;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem