19788-37-5, 4-(Chloromethyl)-3,5-dimethylisoxazole is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
4-Chloromethyl-3,5-dimethylisoxazole (300 mg, 2.07 mmol) was dissolved in dimethyl sulfoxide (3 mL) and sodium cyanide (121 mg, 2.48 mmol) was added at 25C. The reaction was warmed to 60C and reacted for 3 hours. The reaction was cooled to 25C, followed by adding water (10 mL). The reaction was extracted with ethyl acetate (10 mL x 3). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 2-(3,5-dimethylisoxazol-4-yl)acetonitrile (200 mg, as a yellow oil) with a yield of 71%. 1H NMR: (400 MHz, Methanol-d4) delta 3.67(s, 2H), 2.30(s, 3H), 2.28(s, 3H)., 19788-37-5
The synthetic route of 19788-37-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD; WU, Lingyun; CHEN, Xiaoxin; ZHANG, Peng; LIU, Xing; ZHANG, Li; LIU, Zhuowei; CHEN, Shuhui; LONG, Chaofeng; (160 pag.)EP3299371; (2018); A1;,
Isoxazole – Wikipedia
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