Xiong, Qiuju published the artcileEfficacy of continuous lumbar plexus block combined with multimodal analgesia after revision hip arthroplasty, Recommanded Product: Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide, the publication is Chongqing Yike Daxue Xuebao (2017), 42(5), 560-564, database is CAplus.
Objective: To compare the analgesic efficacy between the continuous lumbar plexus block (CLPB) combining with multimodal analgesia and patient controlled i.v. analgesia (PCIA) combining with multimodal analgesia after revision hip arthroplasty. Methods: Totally 68 patients for single side revision hip arthroplasty were equally divided into CLPB group and PCIA group. The parecoxib was used in both group 3 days before operation. The ropivacaine was used to analgesia through lumbar plexus catheterization in CLPB group, and the PCIA group with tramadol and flurbiprofen analgesia. All patients continued analgesia for 3 days. After operation, the parecoxib was used when visual analog scale (VAS) scores more than 3 scores in exercise state. The VAS scores at rest and exercise state were estimated The parecoxib dose by i.v. injection and the presses of the pump were recorded. And the complications were observed Results: The VAS pain scores of CLPB group during rest at different time points after revision hip arthroplasty were significantly lower than those of PCIA group (P<0.05). The VAS scores of CLPB during exercise at 6 h, 12 h, 24 h after revision hip arthroplasty were (2.50±0.71), (3.59±0.99), (3.67±1.01), which were significantly lower than those of (4.97±0.94) (P=0.00), (4.85±0.86) (P=0.00), (4.32±0.73) (P=0.00) in PCIA group at corresponding time points. In CLPB group, the parecoxib dose by i.v. injection and presses of the pump were fewer than that of PCIA group (0.05). And the side effects of CLPB group were fewer than those in PCIA group. Conclusion: CLPB combined with multimodal analgesia can alleviate the early pain of patients undergoing revision hip arthroplasty; the patients who received CLPB technique showed better pain relief, less complication than those who been given PCIA. Therefore, CLPB combined with multimodal analgesia should be considered a better analgesia method for patients after revision hip arthroplasty.
Chongqing Yike Daxue Xuebao published new progress about 198470-85-8. 198470-85-8 belongs to isoxazole, auxiliary class Immunology/Inflammation,COX, name is Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide, and the molecular formula is C8H13ClN2O, Recommanded Product: Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide.
Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
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