Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Chloropyridine 1-oxide, is researched, Molecular C5H4ClNO, CAS is 2402-95-1, about Synthesis of ZPT as a broad-spectrum fungicide.Electric Literature of C5H4ClNO.
In the oxidation catalytic system of maleic anhydride and acetic acid, 2-chloropyridine is converted to ZPT as a raw material. Controlling the thiolation reaction by Na2S-NaSH buffer system, the overall yield is about 75%. The route is suitable for industrial production due to low cost, easy preparation, low risk and high yield.
From this literature《Synthesis of ZPT as a broad-spectrum fungicide》,we know some information about this compound(2402-95-1)Electric Literature of C5H4ClNO, but this is not all information, there are many literatures related to this compound(2402-95-1).
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem