59669-59-9,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.59669-59-9,3-(tert-Butyl)isoxazol-5-amine,as a common compound, the synthetic route is as follows.
To a solution of phosgene (20percent in toluene, 1.13 mL, 2.18 mmol) in CH2Cl2 (20 mL) at 0 ¡ãC was added anh. pyridine (0.176 mL, 2.18 mmol), followed by 5-amino-3-tert-butylisoxazole (0.305 g, 2.18 mmol). The resulting solution was allowed to warm to room temp. over 1 h, and then was concentrated under reduced pressure. The solid residue dried in vacuo for 0.5 h.
As the paragraph descriping shows that 59669-59-9 is playing an increasingly important role.
Reference£º
Patent; Bayer Pharmaceuticals Corp.; EP1047418; (2005); B1;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem