Reference of 3405-77-4, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 3405-77-4, Name is 5-Methylisoxazole-3-carboxylic acid,introducing its new discovery.
Analytical Studies on Isoxazoles. I. A New Colorimetric Determination of 5-Substituted 3-Isoxazolecarboxylic Acids and Their Derivatives
A new colorimetric method for the determination of 5-methyl-3-isoxazolecarboxylic acid (MIA) and 5-phenyl-3-isoxazolecarboxylic acid (PIA) was established.This method is based on the decomposition of 5-substituted 3-isoxazolecarboxylic acids to their corresponding beta-ketonitriles, followed by condensation with p-dimethylaminobenzaldehyde (DABA).The 5-carboxylic isomers caused no interference in the determination of MIA and PIA.Further applications of this method to peroxisal (II), N-<(dimethylamino)carbonyl>-5-methyl-3-isoxazolecarboxamide (III), and 3-(2-oxazolin-2-yl)-5-methylisoxazole (IV), by decomposition to the corresponding 5-substituted 3-isoxazolecarboxylic acids, followed by the color reaction with DABA, are described.Keywords-colorimetric determination; 3-isoxazolecarboxylic acids; p-dimethylaminobenzaldehyde; Knoevenagel condensation reaction; alpha-benzoyl-p-dimethylaminocinnamonitrile; alpha-acetyl-p-dimethylaminocinnamonitrile.
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Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem