One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, COA of Formula: C3H3NO, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 288-14-2, Name is Isoxazole, molecular formula is C3H3NO
The proton affinities (PA’s) of a series of azoles as measured by pulsed high-pressure mass spectrometry are (in kcal/mol) isoxazole, 202.3; oxazole, 207.8; 1,2,4-triazole, 212.4; pyrazole, 212.8; thiazole, 213.2; imidazole, 222.1; 4-methylimidazole, 224.8; 1-methylimidazole, 228.0.Ab initio protonation enthalpies calculated at the MP2/6-31G(d,p) level reproduce the above order and give approximate numerical values.Additionally, these calculations show that the protonation sites are N3 in imidazole and oxazole and N4 in 1,2,4-triazole, the alternate protonationsites of N1, O, and N2, respectively, being less favorable by 53, 57, and 13 kcal/mol.These ab initio studies also indicate a correlation between lone pair n orbital energies and proton affinities.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, COA of Formula: C3H3NO, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 288-14-2
Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem