1123-49-5, Name is 3,5-Dimethyl-4-nitroisoxazole, belongs to isoxazole compound, is a common compound. category: IsoxazolesIn an article, once mentioned the new application about 1123-49-5.
The first example of an “on water” direct catalytic vinylogous Henry addition of 3,5-dialkyl-4-nitroisoxazoles to isatins is described, giving products in excellent yields and up to excellent diastereoselectivities. A remarkable rate-enhancement by water was observed under mild conditions. This approach provides a highly efficient and environmentally benign access to medicinally important isoxazole substituted 3-hydroxy-2-oxindole derivatives.
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Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem