847490-69-1, Name is 4-Iodoisoxazole, belongs to Isoxazoles compound, is a common compound. 847490-69-1In an article, authors is Barak, Dinesh S., once mentioned the new application about 847490-69-1.
Microwave-Assisted Metal-Free Decarboxylative Iodination/Bromination of Isoxazole-4-carboxylic Acids
A microwave-assisted metal-free route to substituted 4-haloisoxazoles via decarboxylative halogenation of substituted isoxazole-4-carboxylic acids using N-iodosuccinimide (NIS) and N-bromosuccinimide (NBS) in the presence of K3PO4 is described. It was discovered that the substitutions present at the 3-position of differently 3,5-disubstituted isoxazoles influenced the outcome of the protocol. The methodology is compatible for performing decarboxylative halogenation followed by decarboxylative Suzuki-Miyaura and Sonogashira couplings as one-pot process.
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Reference£º
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem