With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13999-39-8,3-Amino-4,5-dimethylisoxazole,as a common compound, the synthetic route is as follows.
[18]; 2-(6-Chlorobenzotriazol-l-yl)-l5l5353-tetramethyluronium tetrafluoroborate was used in place of 2-(7-azabenzotriazol-l-yl)-l5l53,3-tetramethyluronium hexafluorophosphate(V) as the coupling agent. The product gave the following characterising data :- 1H NMR Spectrum: (DMSOd6) 1.8 (s, 3H), 2.3 (s, 3H), 3.72 (s, 2H), 3.78 (s, 3H), 6.79 (d, IH)5 6.92 (m, IH)5 7.08 (d, IH)5 7.4 (d, IH)5 8.08 (s, IH)5 8.92 (d, IH)5 9.58 (s, IH)3 10.27 (br s, IH); Mass Spectrum: M+H+ 439 and 441.
13999-39-8, 13999-39-8 3-Amino-4,5-dimethylisoxazole 84148, aIsoxazoles compound, is more and more widely used in various fields.
Reference£º
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2007/113565; (2007); A1;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem