New learning discoveries about 1228689-61-9

1228689-61-9, As the paragraph descriping shows that 1228689-61-9 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.1228689-61-9,Methyl 5-(4-bromophenyl)-3-methylisoxazole-4-carboxylate,as a common compound, the synthetic route is as follows.

Step 4: 5-(4-Bromo-phenyl)-3-methyl-isoxazole-4-carboxylic acid 5-(4-Bromo-phenyl)-3-methyl-isoxazole-4-carboxylic acid methyl ester (39 mmol) in MeOH (50 mL) and H2O (10 mL) was treated with lithium hydroxide (2 g, 48 mmol) and the reaction was stirred at 60 C. for 1 hour. The mixture was acidified, and standard workup provided the title compound.

1228689-61-9, As the paragraph descriping shows that 1228689-61-9 is playing an increasingly important role.

Reference£º
Patent; Amira Phamaceuticals, Inc.; US2011/82181; (2011); A1;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem