5765-44-6, 5-Methylisoxazole is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
5765-44-6, To a solution of 5-methyl isoxazole (5.0 g) in ethyl acetate (100 ml), N-bromo succinate imide (23.6 g) and 2,2′-azobisisobutyronitrile (200 mg) were added to the mixture, and the mixture was refluxed overnight under nitrogen atmosphere. After cooling to 0C, the insolubles were filtered off, the filtrate was washed with an aqueous solution of sodium thiosulfate and saturated brine, and dried over magnesium sulfate. The solvent was distilled off under reduced pressure and the residue was separated and purified by silica gel column chromatography (hexane:ethyl acetate = 10:1), to give 5-bromomethyl isoxazole (1.0 g) as oil. 1H-NMR (200 MHz, CDCl3) delta 4.50 (2H, s), 6.34 (1H, d, J = 1.8 Hz), 8.23 (1H, d, J = 1.8 Hz)
5765-44-6 5-Methylisoxazole 79833, aIsoxazoles compound, is more and more widely used in various fields.
Reference£º
Patent; Takeda Chemical Industries, Ltd.; EP1422228; (2004); A1;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem