Regio- and stereoselective synthesis of 2-alkylidene-hydrofurans by domino-cyclodialkylations of 1,3-dicarbonyl-dianions with 1-bromo-2-chloroethane was written by Langer, Peter;Karime, Inass. And the article was included in Synlett in 2000.SDS of cas: 5765-44-6 This article mentions the following:
Reaction of 1,3-dicarbonyl dianions with 1-bromo-2-chloroethane results in regio- and stereoselective formation of 2-alkylidene-hydrofurans, e.g. I. In the experiment, the researchers used many compounds, for example, 5-Methylisoxazole (cas: 5765-44-6SDS of cas: 5765-44-6).
5-Methylisoxazole (cas: 5765-44-6) belongs to isoxazole derivatives. Isoxazoles present in various natural products and synthetic compounds of biological importance like antibacterial, antagonists, antiinflammatory, analgesics, and also show the applications in functional materials. Isoxazole can be synthesised via a variety of methods. Examples include via the reaction of hydroxylamine with 1,3-diketones or derivatives of propiolic acid.SDS of cas: 5765-44-6
Referemce:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem