β-Methylisoxazole was written by Pino, Piero;Ercoli, Raffaele. And the article was included in Rend. ist. lombardo sci, Pt. I, Classe sci. mat. e nat. in 1955.Product Details of 5765-44-6 This article mentions the following:
The chemical behavior of β-methylisoxazole (I) is similar to that of the α-isomer (II). I is somewhat more stable towards halogenation but is less stable towards alkali than II or the γ-isomer (III) but is more stable than isoxazole. Ring opening occurs by the same mechanism as for I (C.A. 49, 6228i). The following rate constants for the ring opening reaction are (compound and k × 104 l. mole-1 sec.-1 given). I 3.1, II 1.4, III 0.1, IV 4.5. Thus from I and β-phenylisoxazole can be prepared NCCHMeCHO and NCCHPhCHO, resp. In the experiment, the researchers used many compounds, for example, 5-Methylisoxazole (cas: 5765-44-6Product Details of 5765-44-6).
5-Methylisoxazole (cas: 5765-44-6) belongs to isoxazole derivatives. Isoxazole are described as inhibitors of acetylcholinesterase (AChE). Isoxazole ligands bind to and inhibit the Sxc- antiporter. Fe(CO)5 efficiently cleaves the N–O bond of fused isoxazolo-1,4-quinones to give the corresponding imines.All the common reducing reagents failed to open the isoxazole ring.Product Details of 5765-44-6
Referemce:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem