Chen, Li’s team published research in Xiandai Zhenduan Yu Zhiliao in 28 | CAS: 198470-85-8

Xiandai Zhenduan Yu Zhiliao published new progress about 198470-85-8. 198470-85-8 belongs to isoxazole, auxiliary class Immunology/Inflammation,COX, name is Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide, and the molecular formula is C19H17N2NaO4S, Recommanded Product: Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide.

Chen, Li published the artcileAnalysis of effect of oxycodone hydrochloride combined with parecoxib sodium on hyperalgesia after remifentanil combined anesthesia surgery, Recommanded Product: Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide, the publication is Xiandai Zhenduan Yu Zhiliao (2017), 28(13), 2436-2437, database is CAplus.

To study the effect of oxycodone hydrochloride combined with parecoxib sodium on hyperalgesia after remifentanil combined anesthesia surgery. Eighty patients with remifentanil combined anesthesia were selected and randomly divided into group I and group II. Group I received combined remifentanil anesthesia alone, and group II received oxycodone hydrochloride combined with parecoxib sodium. The incidence of adverse reactions such as chills and restlessness, pain score at 0.5-4h postoperatively, and differences in breathing recovery time, extubation time, remifentanil and propofol dosages were compared between the two groups. Compared with group I, the incidence of adverse reactions such as chills and agitation was lower in group II (P < 0.05). The pain score in group II was lower at 0.5-4h after operation (P < 0.05). The breathing recovery time, extubation time, and the dosage of remifentanil and propofol were similar in the two groups (P > 0.05). Oxycodone hydrochloride combined with parecoxib sodium has a great impact on hyperalgesia after remifentanil combined anesthesia surgery, which can effectively play an analgesic effect, reduce postoperative hyperalgesia, and reduce postoperative agitation and other complications.

Xiandai Zhenduan Yu Zhiliao published new progress about 198470-85-8. 198470-85-8 belongs to isoxazole, auxiliary class Immunology/Inflammation,COX, name is Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide, and the molecular formula is C19H17N2NaO4S, Recommanded Product: Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide.

Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem