Wang, Liang published the artcileTransition-Metal-Free Direct Alkylation of Aryl Tetrazoles via Intermolecular Oxidative C-N Formation, Application In Synthesis of 2251-79-8, the publication is Journal of Organic Chemistry (2014), 79(23), 11780-11786, database is CAplus and MEDLINE.
A transition-metal-free synthetic approach for constructing alkylated aryl tetrazoles has been developed using n-Bu4NI as the catalyst and t-BuOOH as the oxidant. It involves the direct C-N bond formation through sp3 C-H activation. A wide range of benzylic C-H substrates (or alkyl ethers) and aryl tetrazoles undergo this reaction smoothly to deliver the corresponding products, e.g., I, in good yields.
Journal of Organic Chemistry published new progress about 2251-79-8. 2251-79-8 belongs to isoxazole, auxiliary class Trifluoromethyl,Fluoride,Benzene, name is 5-(4-(Trifluoromethyl)phenyl)-1H-tetrazole, and the molecular formula is C5H10Cl3O3P, Application In Synthesis of 2251-79-8.
Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem