2510-36-3, 3,5-Dimethylisoxasole-4-carboxylic acid is a Isoxazoles compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Compound 1f (R1=4-Cl, R2=6-Br, X=O) (70 mg, 0.16 mmol),3,5-Dimethylisoxazole-4-carboxylic acid (31 mg, 0.22 mmol),1-hydroxybenzotriazole (HOBt) (30 mg, 0.22 mmol) and1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDCI) (42 mg, 0.22 mmol),in room temperature,The reaction was carried out in anhydrous dichloromethane (5 ml) for 12 hours.Wash with saturated brine,Extracted with dichloromethane,Dry over anhydrous sodium sulfate,The organic layer was separated by silica gel column chromatography.Obtained a pale yellow powder of 37 mg.The yield was 41%., 2510-36-3
As the paragraph descriping shows that 2510-36-3 is playing an increasingly important role.
Reference£º
Patent; Sun Yat-sen University; Zhang Hui; Bai Chuan; Pan Ting; Wu Liyang; (17 pag.)CN108610301; (2018); A;,
Isoxazole – Wikipedia
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