Liu, Guo-yan published the artcileEffect of parecoxib sodium combination of laryngeal mask airway on reaction of emergence agitation undergoing laparoscopic cholecystectomy, Computed Properties of 198470-85-8, the publication is Zhongguo Zhongxiyi Jiehe Waike Zazhi (2014), 20(2), 146-148, database is CAplus.
The effect of parecoxib sodium combination of the laryngeal mask airway on the reaction of emergence agitation undergoing laparoscopic cholecystectomy was observed Forty-five patients were randomly divided into group I (endotracheal extubation), group II (the laryngeal mask airway) and group III (parecoxib sodium combination of the laryngeal mask airway). Group I and II were given i.v. injection of normal saline 10mL and group III was given i.v. injection of parecoxib sodium 40 mg, 15 min before surgery. Sedation score was obviously higher in group II and group III than in group I (P<0.05); Agitation score was obviously lower in group II and group III than in group I (P<0.05); vital signs in group II and group III were stable than in group I before anesthesia, endotracheal extubation and after extubation (P<0.05) and vital signs were more stable in group III (P<0.05). Parecoxib sodium combination of the laryngeal mask airway can effectively and safely prevent emergence agitation undergoing laparoscopic cholecystectomy.
Zhongguo Zhongxiyi Jiehe Waike Zazhi published new progress about 198470-85-8. 198470-85-8 belongs to isoxazole, auxiliary class Immunology/Inflammation,COX, name is Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide, and the molecular formula is C19H17N2NaO4S, Computed Properties of 198470-85-8.
Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem