Sakharov, Pavel A.’s team published research in RSC Advances in 9 | CAS: 1076-59-1

RSC Advances published new progress about 1076-59-1. 1076-59-1 belongs to isoxazole, auxiliary class Oxazoline,Benzene,Ester, name is 3-Phenylisoxazol-5(2H)-one, and the molecular formula is C9H7NO2, Synthetic Route of 1076-59-1.

Sakharov, Pavel A. published the artcileNon-natural 2H-azirine-2-carboxylic acids: an expedient synthesis and antimicrobial activity, Synthetic Route of 1076-59-1, the publication is RSC Advances (2019), 9(65), 37901-37905, database is CAplus and MEDLINE.

Non-natural 2H-azirine-2-carboxylic acids I (R1 = CH3, C6H5, 2-furyl, etc.; R2 = H, CH3, C6H5, 4-BrC6H4, CH2CCH) were obtained in high yields by FeCl2-catalyzed isomerization of 5-chloroisoxazoles II to azirine-2-carbonyl chlorides followed by their hydrolysis. The 3-aryl- and 3-heteroaryl-substituted acids I are stable during prolonged storage, exhibit antibacterial activity against ESKAPE pathogens and show a low level of cytotoxicity.

RSC Advances published new progress about 1076-59-1. 1076-59-1 belongs to isoxazole, auxiliary class Oxazoline,Benzene,Ester, name is 3-Phenylisoxazol-5(2H)-one, and the molecular formula is C9H7NO2, Synthetic Route of 1076-59-1.

Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem