Long, Hao published the artcileSafety and efficacy of parecoxib sodium in multimode analgesia after osteoarticular surgery, HPLC of Formula: 198470-85-8, the publication is Zhongguo Jiaoxing Waike Zazhi (2014), 22(5), 458-460, database is CAplus.
Objective: To evaluate the safety and efficacy of parecoxib sodium in multimode analgesia after osteoarticular surgery. Methods: 90 patients were divided into group A (parecoxib sodium combined with fentanyl PCIA) and group B (fentanyl PCIA). Group A is further divided into group A 1: venous group (40 mg/time, 1 time/12 h i.v. infusion) and A 2 group: s.c. injection group (40 mg/ time 1 time /12 h). The VAS score, fentanyl dosage and ADR, PCA press number and effective number of each group at 48 h postoperatively were compared. Results: Group A and group B had statistically significant difference in VAS score, fentanyl dosage and ADR, PCA press number and effective (P < 0.05 ). In group A, the venous group and s.c. injection group had no statistically significant difference (P>0.05). Conclusion: The parecoxib sodium combined with PCA multimode analgesia can reduce fentanyl dose and alleviate pain at 48 h postoperatively.
Zhongguo Jiaoxing Waike Zazhi published new progress about 198470-85-8. 198470-85-8 belongs to isoxazole, auxiliary class Immunology/Inflammation,COX, name is Sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide, and the molecular formula is C19H17N2NaO4S, HPLC of Formula: 198470-85-8.
Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem