Khutorianskyi, Andrii published the artcileDifluoromethyl Nitrile Oxide (CF2HCNO): A Neglected Chemical Reagent, Quality Control of 1935503-24-4, the publication is European Journal of Organic Chemistry (2017), 2017(27), 3935-3940, database is CAplus.
The synthesis of CF2H-isoxazoles I [R = CN, C(O)CH3, CO2Me, etc.] via [3+2]-cycloaddition of a novel chem. reagent – difluoromethyl nitrile oxide (CF2HCNO) in-situ generated from difluoromethylacetaldehyde oximes with alkynes/enamines was reported. These products were promising cores for agrochem. A representative CHF2-isoxazole was incorporated into the known fungicide Fluxapyroxad and the synthesized analog showed higher antifungal activity than the parent fungicide.
European Journal of Organic Chemistry published new progress about 1935503-24-4. 1935503-24-4 belongs to isoxazole, auxiliary class Difluoromethylated Building Blocks, name is 3-(Difluoromethyl)isoxazole-5-carboxylic acid, and the molecular formula is C5H3F2NO3, Quality Control of 1935503-24-4.
Referemce:
https://en.wikipedia.org/wiki/Isoxazole,
Isoxazole | C3H3NO – PubChem