Beccalli, Egle M.’s team published research in Journal of Organic Chemistry in 1985 | CAS: 29278-09-9

Ethyl 5-amino-3-phenylisoxazole-4-carboxylate(cas: 29278-09-9) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.Formula: C12H12N2O3

Beccalli, Egle M.; Manfredi, Amadea; Marchesini, Alessandro published an article in Journal of Organic Chemistry. The title of the article was 《Alkynes from 5-aminoisoxazoles》.Formula: C12H12N2O3 The author mentioned the following in the article:

Diazotization of 5-aminoisoxazoles I [R = Ph, H, CO2Et, Me; R1 = CONH2, CO2Et, p-O2NC6H4, 4-pyridyl, etc. (≥1 of R and R1 is an electron-withdrawing group)] by reaction with NaNO2 in AcOH-H2O afforded the corresponding RCCR1. A reaction path involving an intermediate isoxazol-5-yl radical is proposed. In the part of experimental materials, we found many familiar compounds, such as Ethyl 5-amino-3-phenylisoxazole-4-carboxylate(cas: 29278-09-9Formula: C12H12N2O3)

Ethyl 5-amino-3-phenylisoxazole-4-carboxylate(cas: 29278-09-9) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.Formula: C12H12N2O3

Referemce:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem