The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 3,5-Dimethyl-4-nitropyridine 1-oxide( cas:14248-66-9 ) is researched.Application of 14248-66-9.Johnson, Colin David; Katritzky, Alan R.; Shakir, Naeem published the article 《Acidity functions and the protonation of weak bases. VI. Amide acidity function. Its extension and application to N-oxides》 about this compound( cas:14248-66-9 ) in Journal of the Chemical Society [Section] B: Physical Organic. Keywords: AMIDE ACIDITY FUNCTION; PYRIDINE OXIDE PROTONATION; PROTONATION PYRIDINE OXIDE. Let’s learn more about this compound (cas:14248-66-9).
The protonation of pyridine 1-oxides of low basicity in aqueous H2SO4 is correlated by the amide acidity function rather than the Hammett acidity function. The HA-scale was extended by measurements of the second protonation of phenazine 5,10-dioxide (I).
Although many compounds look similar to this compound(14248-66-9)Application of 14248-66-9, numerous studies have shown that this compound(SMILES:O=[N+](C1=C(C)C=[N+]([O-])C=C1C)[O-]), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem