So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Rmedi, Hamdi researched the compound: 2,3-Dibromo-1-propanol( cas:96-13-9 ).COA of Formula: C3H6Br2O.They published the article 《Design and synthesis of fused cyclic sulfamides-oxazolidinones》 about this compound( cas:96-13-9 ) in Tetrahedron. Keywords: sulfamoyloxazolidinone preparation; carboxylsulfamide preparation kinetic intramol cyclization. We’ll tell you more about this compound (cas:96-13-9).
An efficient protocol for the synthesis of a new series of oxazolidin-2-ones containing sulfamide moieties I (R = Pr, cyclopentyl, Ph, benzyl, etc.) is described. The synthesis was achieved in two reaction steps. The first was carried out under anhydrous conditions at 0 °C through a selective addition of 2,3-dibromopropanol and primary amines RNH2 to chlorosulfonylisocyanate to produce N-carboxylsulfamides RNHS(O)2NHC(O)OCH2CH(Br)CH2Br in good yields. Under appropriate conditions of solvent, base and temperature, these intermediates underwent subsequent intramol. cyclization, giving exclusively the corresponding sulfamoyloxazolidinones.
Here is just a brief introduction to this compound(96-13-9)COA of Formula: C3H6Br2O, more information about the compound(2,3-Dibromo-1-propanol) is in the article, you can click the link below.
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem