Reference of 3,5-Dimethyl-4-nitropyridine 1-oxide. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: 3,5-Dimethyl-4-nitropyridine 1-oxide, is researched, Molecular C7H8N2O3, CAS is 14248-66-9, about Titanium(0) reagents. III. A convenient preparation of 4-pyridinamine derivatives. Author is Malinowski, Marek; Kaczmarek, Lukasz.
Ti(0) slurry, easily accessible by the reduction of TiCl4 with LiAlH4 or Mg in THF, is an excellent reagent for the reduction of N-nitropyridine N-oxides, e.g., I (R = H, Me, F, Cl) to 4-aminopyridines, e.g., II. The reaction proceeds smoothly and fast at room temperature giving the amines in >90% yields.
There is still a lot of research devoted to this compound(SMILES：O=[N+](C1=C(C)C=[N+]([O-])C=C1C)[O-])Reference of 3,5-Dimethyl-4-nitropyridine 1-oxide, and with the development of science, more effects of this compound(14248-66-9) can be discovered.
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem