The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Chloropyridine 1-oxide( cas:2402-95-1 ) is researched.Related Products of 2402-95-1.Liu, Rui; Liu, Shan; Zhu, Hongjun published the article 《Synthesis of 2-mercaptopyridine-1-oxide zinc salt and its crystal structure》 about this compound( cas:2402-95-1 ) in Nanjing Gongye Daxue Xuebao, Ziran Kexueban. Keywords: mercaptopyridine oxide zinc salt synthesis chloropyridine crystal structure. Let’s learn more about this compound (cas:2402-95-1).
2-Chloropyridine-N-oxide was synthesized by treating 2-chloropyridine with hydrogen peroxide in glacial acetic acid. The final product 2-mercaptopyridine-1-oxide zinc salt was obtained from 2-chloropyridine-N-oxide via reaction with NaSH, preparation of the sodium salt and chelation with ZnSO4. The structure of the product was characterized by m.p., 1HNMR and single crystal diffractometer. The crystal belonged to monoclinic space group of P21/C with a = 0.84010(17) nm, b = 1.0184(2) nm, c = 1.3736(3) nm, α = 90.00°, β = 97.23(3)°, γ = 90.00°, Dx = 1.810 g/cm3, Z = 4, F(000) = 640, μ = 2.453 mm-1, and the final deviation factor R = (0.0325) and wR = (0.0728).
There is still a lot of research devoted to this compound(SMILES：ClC1=CC=CC=[N+]1[O-])Related Products of 2402-95-1, and with the development of science, more effects of this compound(2402-95-1) can be discovered.
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem