Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Zeitschrift fur medizinische Physik called Comparison of CBCT conversion methods for dose calculation in the head and neck region., Author is Irmak, Sinan; Georg, Dietmar; Lechner, Wolfgang, which mentions a compound: 96-13-9, SMILESS is OCC(Br)CBr, Molecular C3H6Br2O, Reference of 2,3-Dibromo-1-propanol.
The purpose of this study was to compare different methods of CBCT conversion respect to dose calculation accuracy. Twelve head and neck cancer patients treated with VMAT using simultaneous integrated boost technique were selected for the study. For each patient a planning CT (pCT), a control. CT acquired in the fourth week of treatment and a CBCT scan acquired on the closest day with the control CT were used. In order to re-calculate dose directly on CBCT image sets, a population based approach (CBCTPop) and a Histogram Matching (HM) approach based on rigid (CBCTHM-R) and deformable registration (CBCTHM-D) were used. Additionally, virtual CTs (vCTs) were generated using two deformable image registration algorithms (CTELX and CTANC) of the planning CT to the CBCT by using two different deformable image registration (DIR) algorithms. The corresponding control CTs were selected as ground truth and dose distributions on CBCT were analyzed using 3D global gamma index analysis applying a threshold of 10% with respect to the prescribed dose. Using the 2%/2mm gamma criterion, the results were 89.9%(±8.3%), 94.1%(±5.0%), 94.3%(±5.7%), 96.1%(±3.9%), 93.4%(±6.3%) for the CBCTPop, CBCTHM-R, CBCTHM-D, CTELX and CTANC, respectively. On average, the HM and DIR techniques showed a higher accuracy compared to the population based approach, but Kruskal-Wallis test did not show significant difference among the investigated dose calculation techniques assuming p<0.05. More sophisticated CBCT dose calculation methods seem to improve the dose calculation accuracy, but statistical significance remains to be demonstrated. There is still a lot of research devoted to this compound(SMILES：OCC(Br)CBr)Reference of 2,3-Dibromo-1-propanol, and with the development of science, more effects of this compound(96-13-9) can be discovered.
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem