In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Titanium(0) reagents. III. A convenient preparation of 4-pyridinamine derivatives, published in 1988, which mentions a compound: 14248-66-9, mainly applied to nitropyridine oxide reduction titanium; pyridinamine, Application of 14248-66-9.
Ti(0) slurry, easily accessible by the reduction of TiCl4 with LiAlH4 or Mg in THF, is an excellent reagent for the reduction of N-nitropyridine N-oxides, e.g., I (R = H, Me, F, Cl) to 4-aminopyridines, e.g., II. The reaction proceeds smoothly and fast at room temperature giving the amines in >90% yields.
In some applications, this compound(14248-66-9)Application of 14248-66-9 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem