The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Chloropyridine 1-oxide( cas:2402-95-1 ) is researched.Related Products of 2402-95-1.Johnson, Colin David; Katritzky, Alan R.; Shakir, Naeem published the article 《Acidity functions and the protonation of weak bases. VI. Amide acidity function. Its extension and application to N-oxides》 about this compound( cas:2402-95-1 ) in Journal of the Chemical Society [Section] B: Physical Organic. Keywords: AMIDE ACIDITY FUNCTION; PYRIDINE OXIDE PROTONATION; PROTONATION PYRIDINE OXIDE. Let’s learn more about this compound (cas:2402-95-1).
The protonation of pyridine 1-oxides of low basicity in aqueous H2SO4 is correlated by the amide acidity function rather than the Hammett acidity function. The HA-scale was extended by measurements of the second protonation of phenazine 5,10-dioxide (I).
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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem