The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1-Piperidineacetic Acid( cas:3235-67-4 ) is researched.Application In Synthesis of 1-Piperidineacetic Acid.Gan, Liangbing; Jiang, Jianfeng; Zhang, Wen; Su, Yang; Shi, Yaru; Huang, Chunhui; Pan, Jinqi; Lue, Mujian; Wu, Yi published the article 《Synthesis of Pyrrolidine Ring-Fused Fullerene Multicarboxylates by Photoreaction》 about this compound( cas:3235-67-4 ) in Journal of Organic Chemistry. Keywords: fullerene photoreaction aminopolycarboxylate; pyrrolidine fused fullerene polycarboxylate preparation. Let’s learn more about this compound (cas:3235-67-4).
Aminopolycarboxylic esters react with C60 under photolysis to produce fullerene multicarboxylates. Irradiation of tetra-Me ethylenediaminetetraacetate (EDTA) with C60 yields the EDTA-containing fullerene monoadduct C60(MeOOCCH)2NCH2CH2N(CH2COOMe)2. In addition, several other C60 monoadducts are also isolated and characterized, including compounds due to EDTA fragmentation. Similar results are observed with pentamethyl dimethylenetriaminepentaacetate (DTPA). When partially methylated nitrilotriacetic acid is irradiated with C60, decarboxylation occurs and organodihydrofullerene derivatives such as C60(H)[CH2N(CH2COOMe)2] are formed. Radical mechanisms are proposed for both types of photoreactions. The fullerene derivatives are characterized by their spectroscopic data. Photoreactions of C60 with other analogous mols. also support the conclusions.
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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem