Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2,3-Dibromo-1-propanol, is researched, Molecular C3H6Br2O, CAS is 96-13-9, about The synthetic protocol for α-bromocarbonyl compounds via brominations.Product Details of 96-13-9.
Tech. information for the convenient one-pot bromination followed by esterification or amidation to prepare various functionalized a-bromocarbonyl compounds possessing tertiary-alkyl moieties I [R1 = R2 = Me, Et, n-Pr, n-Bu; R1R2 = (CH2)3, (CH2)4, (CH2)5; R3 = O(CH2)3OH, C6H5NH, 4-CHOC6H4O, etc.] was summarized. Bromination reaction using bromine was sometimes problematic but these robust protocols would be effective information for chemists who needs abromocarbonyl compounds
As far as I know, this compound(96-13-9)Product Details of 96-13-9 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem