The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《The stability of metal complexes of 1,4-piperazinediacetic acid》. Authors are Irving, H.; Pettit, L. D..The article about the compound:1-Piperidineacetic Acidcas:3235-67-4,SMILESS:OC(=O)CN1CCCCC1).Application of 3235-67-4. Through the article, more information about this compound (cas:3235-67-4) is conveyed.
1,4-Piperazinediacetic acid has been prepd and its acid dissociation constants have been measured at 20° and μ = 0.1M KCl. Values for the stability constants of its complexes with Mg, Ca, Sr, Ba, Ni, Cu(II), and Zn have been measured and are compared with corresponding data for 1-piperidine-acetic acid and other ligands of related structure. It is concluded that chelation involving both N atoms of the piperazine derivative does not occur with small ions.
From this literature《The stability of metal complexes of 1,4-piperazinediacetic acid》,we know some information about this compound(3235-67-4)Application of 3235-67-4, but this is not all information, there are many literatures related to this compound(3235-67-4).
Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem