With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.53983-15-6,Ethyl 5-amino-4-phenylisoxazole-3-carboxylate,as a common compound, the synthetic route is as follows.,53983-15-6
5-amino-obtained Example 2 The 4-phenyl-isoxazole-3-carboxylic acid ethyl ester A1 (0.464g, 2mol), benzaldehyde(0.212g, 2mol) and 10mL absolute ethanol, was added one drop of concentrated sulfuric acid as a catalyst, was heated to reflux, TLC monitoring of the reaction,After completion of the reaction, cooled to room temperature, suction filtered, washed with water and purified by column chromatography to give a white powdery solid 0.45g. Yield 71.77%.
As the paragraph descriping shows that 53983-15-6 is playing an increasingly important role.
Reference£º
Patent; Shenyang Pharmaceutical University; Xu, Wei; Chen, Yu; Zhang, Rui; (15 pag.)CN105777661; (2016); A;,
Isoxazole – Wikipedia
Isoxazole | C3H3NO – PubChem