S-21 News Final Thoughts on Chemistry for 33282-15-4

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33282-15-4, Name is 5-(4-Hydroxyphenyl)isoxazole-3-carboxylic acid, belongs to isoxazole compound, is a common compound. HPLC of Formula: C10H7NO4In an article, once mentioned the new application about 33282-15-4.

The treatment of secondary amines with chloroform in the presence of KF-Al2O3 in acetonitrile brought about highly facile and efficient N-formylation to give the corresponding formamides in good to excellent yields. The N-formylation reaction not only involves mild conditions, simple operations and high yields but high chemoselectivity as well.

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Reference:
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem