Electric Literature of 33282-15-4, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.33282-15-4, Name is 5-(4-Hydroxyphenyl)isoxazole-3-carboxylic acid, molecular formula is C10H7NO4. In a Article，once mentioned of 33282-15-4
We describe the catalytic amination of beta-(hetero)arylethyl ethers with amines using the organic superbase t-Bu-P4 to obtain beta-(hetero)arylethylamines. The reaction has a broad substrate scope and allows the transformations of electron-deficient and electron-neutral beta-(hetero)arylethyl ethers with various amines including pyrrole, N-alkylaniline, diphenylamine, aniline, indole, and indoline derivatives. Mechanistic studies indicate a two-reaction pathway of MeOH elimination from the substrate to form a (hetero)arylalkene followed by the hydroamination of the alkene.
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Reference：
Isoxazole – Wikipedia,
Isoxazole | C3H3NO – PubChem